By Gianfranco Donelli (eds.)
The Advances in Microbiology, Infectious ailments and Public future health sequence will supply microbiologists, hygienists, epidemiologists and infectious ailments experts with well-chosen contributed volumes containing up-to-date details within the components of uncomplicated and utilized microbiology related to appropriate concerns for public health and wellbeing, together with bacterial, fungal and parasitic infections, zoonoses and anthropozoonoses, environmental and meals microbiology.
The expanding hazard of the multidrug-resistant microorganisms and the similar host immune reaction, the hot techniques for the therapy of biofilm-based, acute and protracted microbial infections, in addition to the improvement of recent vaccines and extra efficacious antimicrobial medicinal drugs to avoid and deal with human and animal infections should be additionally reviewed during this sequence within the gentle of the newest achievements in those fields.
distinctive recognition might be dedicated to the short diffusion all over the world of the recent findings of the main complex translational researches performed within the assorted fields of microbiological sciences, with the purpose to advertise a suggested validation and move at medical point of the main promising experimental results.
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Extra info for Advances in Microbiology, Infectious Diseases and Public Health: Volume 4
Upregulation of cytoprotective genes (Hooper et al. 2001; Lin et al. 2008). Prevention of apoptosis and cell death (Lin et al. 2008; Khailova et al. 2010). Immunological mechanisms: stimulation of specific antibody-secreting cell response (Kaila et al. 1992), enhancement of pathogen phagocytosis (Schiffrin et al. 1997), and modification of cytokine production (Miettinen et al. 1996; Truusalu et al. 2010). Induction of the expression of tight junction proteins necessary for barrier function (Khailova et al.
However, we observed no resistance to erythromycin and chloramphenicol, and only one L. buchneri strain was resistant to tetracycline; it was excluded from further experiments. In the case of L. fermentum species, a natural resistance to trimethoprim plus sulfamethoxazole, metronidazole, fluoroquinolones, and cefoxitin was interpreted as a high natural resistance to these antibiotics. In critically ill patients, the prophylactic selective decontamination of the digestive tract simultaneously involves applying three to four different antimicrobials (vancomycin, cefoxitin, ciprofloxacin, and some new tetracyclines; also the combination of metronidazole with cephalosporins or fluoroquinolones) for the suppression of potentially pathogenic microorganisms (Solomkin et al.
2014). The origin of the strain (biotope/host specificity), its colonizing ability, and its safety and efficacy serve as the basic criteria for defining suitable candidates for probiotics. Currently, according to well-designed clinical trials, systematic reviews, and meta-analysis, the efficacy of probiotics has been addressed as a general class (Hill et al. 2014). The main contribution of probiotics is to a healthy gut microbiota or/and nutrition benefit. The support of probiotics for a healthy immune system has also been acknowledged by several authors as a core benefit while considering the specificity of strains with differential immune pro- or antiinflammatory action (Hill et al.
Advances in Microbiology, Infectious Diseases and Public Health: Volume 4 by Gianfranco Donelli (eds.)